Successful Treatment of Unscheduled Uterine Bleeding During Transdermal Menopausal Hormone Therapy Combined With Bazedoxifene Cureus 17: e81582／ 英文学術誌／
Koike T, Koike K, Shiga T, Takenaka M, Furui T
2023年
Evaluation of the Relationship Between Equol Production and the Risk of Locomotive Syndrome in Very Elderly Women International Journal of Probiotics and Prebiotics 18: 7–13／ 英文学術誌／
Koike T, Yamamoto S, Furui T, Miyazaki C, Ishikawa H, Morishige K-I
2022年
Intracellular ferritin heavy chain plays the key role in artesunate-induced ferroptosis in ovarian serous carcinoma cells J Clin Biochem Nutr 25: 34–40／ 英文学術誌／
Koike T, Takenaka M, Suzuki N, Ueda Y, Mori M, Hirayama T, Nagasawa H, Morishige K-I
2021年
Effect of Chicken Extract on Breast Milk Production in Primiparous Mothers in Japan: A Randomized Clinical Trial Int J Probio Prebio 16: 16–21／ 英文学術誌／
Awano M, Koike K, Sawda T, Feng Hao XU, Suzuki N
Porcine placental extract modulates monocytic immune responses in vitro and in postmenopausal women J Jpn Complement Altern Med 18: 7–21／ 英文学術誌／
Koike K, Yoshikawa C, Ishigaki Y, Suzuki N, Sugiura K, Koike T, Takano F
2013年
Efficacy of porcine placental extract on climacteric symptoms in peri- and post-menopausal women Climacteric 16: 28–35／ 英文学術誌／
Koike K, Yamamoto Y, Suzuki N, Yamazaki R, Yoshikawa C, Takano F, Takuma K, Sugiura K, Inoue M
Efficacy of porcine placental extract on shoulder stiffness in climacteric and postmenopausal women with hormone therapy Climacteric 16: 447–452／ 英文学術誌／
Koike K, Yamamoto Y, Suzuki N, Yamazaki R, Yoshikawa C, Takano F, Sugiura K, Inoue M
2012年
Placental extract improves hippocampal neuronal loss and fear memory impairment resulting from chronic restraint stress in ovariectomized mice J Pharmacol Sci 120: 89–97／ 英文学術誌／
Takuma K, Funatsu Y, Mizoguchi H, Kitahara Y, Ibi D, Kamei H, Kaku T, Matsuda T, Koike K, Inoue M, Nagai T, Yamada K
Efficacy of porcine placental extracts with hormone therapy for postmenopausal women with knee pain Climacteric 15: 30–35／ 英文学術誌／
Koike K, Yamamoto Y, Suzuki N, Yamazaki R, Yoshikawa C, Takuma K, Sugiura K, Inoue M
Combination of chronic stress and ovariectomy causes conditioned fear memory deficits and hippocampal cholinergic neuronal loss in mice Neuroscience 207: 261–273／ 英文学術誌／
Takuma K, Mizoguchi H, Funatsu Y, Hoshina Y, Himeno Y, Fukuzaki E, Kitahara Y, Arai S, Ibi D, Kamei H, Matsuda T, Koike K, Inoue M, Nagai T, Yamada K
2008年
Pycnogenol, French Maritime Pine Bark Extract, significantly lowers requirement of analgesic medication in dysmenorrhea: a multi-center, randomized, double-blind, placebo-controlled study J Reprod Med 53: 338–346／ 英文学術誌／
Suzuki N, Uebaba K, Kohama T, Noniwa N, Kanatama N, Koike K
Enhanced activity of hippocampal BACE in a mouse model of postmenopausal memory deficits Neurosci Lett 433: 141–145／ 英文学術誌／
Fukuzaki E, Takuma K, Funatsu Y, Himeno Y, Yoshida S, Kitahara Y, Gu B, Mizoguchi H, Ibi D, Koike K, Inoue M, Yamada K
Ovariectomy increases neuronal amyloid-β binding alcohol dehydrogenase level in the mouse hippocampus Neurochem Int 52: 1358–1364／ 英文学術誌／
Fukuzaki E, Takuma K, Himeno Y, Yoshida S, Funatsu Y, Kitahara Y, Mizoguchi H, Ibi D, Koike K, Inoue M, Yamada K
Ginkgo biloba extract EGb 761 attenuates hippocampal neuronal loss and cognitive dysfunction resulting from chronic restraint stress in ovariectomized rats Neuroscience 149: 256–262／ 英文学術誌／
Takuma K, Hoshina Y, Arai S, Himeno Y, Matsuo Y, Funatsu Y, Kitahara Y, Ibi D, Hayase H, Kamei H, Mizoguchi H, Nagai T, Koike K, Inoue M, Yamada K
2007年
17β-Estradiol attenuates hippocampal neuronal loss and cognitive dysfunction induced by chronic restraint stress in ovariectomized rats Neuroscience 146: 60–68／ 英文学術誌／
Takuma K, Matsuo A, Himeno Y, Hoshina Y, Ohno Y, Funatsu Y, Arai H, Kamei H, Mizoguchi H, Nagai T, Koike K, Inoue M, Yamada K
2006年
Colestilan, a new bile acid sequestering resin, reduces body weight in postmenopausal women who have dieted unsuccessfully Drugs in R & D 6: 1–7／ 英文学術誌／
Koike K, Murakami K, Nozaki N, Sugiura K, Inoue M
2004年
Efficacy of the Herbal Medicine Unkei-to as an Adjunctive Treatment to Hormone Replacement Therapy for Postmenopausal Women With Depressive Symptoms Clin Neuropharmacol 27: 157–162／ 英文学術誌／
Koike K, Ohno S, Takahashi N, Suzuki N, Nozaki N, Murakami K, Sugiura K, Yamada K, Inoue M
Effects of the traditional Japanese medicine Unkei-to on the corticotropin-releasing factor-induced increase in locomotor activity Pharmacol Biochem Behav 78: 799–803／ 英文学術誌／
Terawaki K, Koike K, Yuzurihara M, Kase Y, Takeda S, Aburada M, Murakami K, Ohno S, Suzuki N, Inoue M
Expression of estrogen receptor-beta in the postischemic monkey hippocampus Neurosci Lett 369: 9–13／ 英文学術誌／
Takahashi N, Tonchev A, Koike K, Murakami K, Yamada K, Yamashima T, Inoue M
Correlation of histological localization of tumor-associated macrophages with clinicopathological features in endometrial cancer Anticancer Res 24: 3335–3342／ 英文学術誌／
Ohno S, Ohno Y, Suzuki N, Kamei T, Koike K, Inagawa H, Kohchi C, Soma G, Inoue M
The factor relating ego in middle aged women going regularly to gynecology J Jpn Menopause Soc 12: 42–47／ 英文学術誌／
Sakai A, Sekizuka N, Shimada K, Tabuchi N, Kameda Y, Sasagawa T, Koike K, Bouda H
2003年
Accumulation of microglial cells expressing ELR motif-positive CXC chemokines and their receptor CXCR2 in monkey hippocampus after ischemia-reperfusion Brain Res 970: 195–204／ 英文学術誌／
Popivanova B, Koike K, Tonchev A, Ishida Y, Kondo T, Ogawa S, Mukaida N, Inoue M, Yamashima T
2002年
Tamoxifen regulates human telomerase reverse transcriptase (hTERT) gene expression differently in breast and endometrial cancer cells Oncogene 21: 3517–3524／ 英文学術誌／
Wang Z, Kyo S, Maida Y, Takakura M, Tanaka M, Yatabe N, Koike K, Hayakawa J, Ohmichi M, Inoue M
2001年
An inhibitory effect of cytokine-induced neutrophil chemoattractant on corticotropin-releasing factor-induced increase in locomotor activity Brain Res 917: 133–137／ 英文学術誌／
Terawaki K, Koike K, Yuzurihara M, Kurauchi K, Ishige A, Sasaki H, Murakami K, Inoue M
Vestibular modulation of plasma vasopressin levels in rats Brain Res 914: 179–184／ 英文学術誌／
Horii A, Koike K, Uno A, Uno Y, Kubo T
2000年
Involvement of extracellular signal-regulated protein kinase in gliosis induced during recovery from metabolic inhibition Biochem Biophys Res Commun 267: 892–896／ 英文学術誌／
Masuhara K, Ohmichi M, Kurachi H, Tasaka K, Kanzaki T, Kimura A, Hayakawa J, Hisamoto K, Koike K, Murata Y
Progesterone regulates human telomerase reverse transcriptase gene expression via activation of mitogen activated protein kinase signaling pathway Cancer Res 60: 5376–5381／ 英文学術誌／
Wang Z, Kyo S, Takakura M, Tanaka M, Yatabe N, Maida Y, Fujiwara M, Hayakawa J, Ohmichi M, Koike K, Inoue M
1999年
Mitogen-activated protein kinase cascade is involved in endothelin-1-induced rat puerperal uterine contraction Endocrinology 140: 722–731／ 英文学術誌／
Kimura A, Ohmichi M, Takeda T, Kurachi H, Ikegami H, Koike K, Masuhara K, Hayakawa J, Kanzaki T, Kobayashi M, Akabane M, Inoue M, Miyake A, Murata Y
Insulin-induced hypoglycemia activates a chemokinergic neuronal pathway in the hypothalamo-pituitary system Neuropeptides 33: 271–275／ 英文学術誌／
Osako Y, Koike K, Kiyama H, Sakamoto Y, Segawa T, Inoue M, Murata Y
Changes with aging of steroidal levels in the cerebrospinal fluid of women Maturitas 33: 71–80／ 英文学術誌／
Murakami K, Nakagawa T, Shozu M, Uchide K, Koike K, Inoue M
1998年
Evidence that folliculo-stellate cells mediate the inhibitory effect of Japanese kampo medicine, Unkei-to, on growth hormone secretion in rat anterior pituitary cell cultures Am J Reprod Immunol 39: 217–222／ 英文学術誌／
Koike K, Zhang ZX, Sakamoto Y, Miyake A, Inoue M
The herbal medicine Unkei-to stimulates CINC production in the pituitary folliculo-stellate-like cell line (TtT/GF) Am J Reprod Immunol 39: 249–255／ 英文学術誌／
Koike K, Zhang ZX, Sakamoto Y, Jikihara H, Masuhara K, Murakami K, Miyake A, Inoue M
1997年
Pituitary folliculo-stellate-like cell line (TtT/GF) produces a cytokine-induced neutrophil chemoattractant Neuropeptide 31: 46–51／ 英文学術誌／
Zhang ZX, Koike K, Sakamoto Y, Jikihara H, Kanda Y, Inoue K, Hirota K, Miyake A
The role of MAP kinase pathway in PGF2α-induced rat puerperal uterine contraction Endocrinology 138: 3103–3111／ 英文学術誌／
Ohmichi M, Koike K, Kimura A, Masuhara K, Ikegami H, Ikebuchi Y, Kanzaki T, Touhara K, Sakaue M, Kobayashi Y, Akabane A, Miyake A, Murata Y
Prolactin stimulates mitogen-activated protein kinase in human leiomyoma cells Biochem Biophys Res Commun 238: 473–477／ 英文学術誌／
Nohara A, Ohmichi M, Koike K, Jikihara H, Kimura A, Masuhara K, Ikegami H, Inoue M, Miyake A, Murata Y
Norepinephrine stimulates mitogen-activated protein kinase activity in GT1-1 GnRH neuronal cell lines Endocrinology 138: 5275–5281／ 英文学術誌／
Sawada T, Ohmichi M, Koike K, Kanda Y, Kimura A, Masuhara K, Ikegami H, Inoue M, Miyake A, Murata Y
The pituitary folliculo-stellate cell line TtT/GF augments basal and TRH-induced prolactin secretion by GH3 cells Life Sci 61: 2491–2497／ 英文学術誌／
Koike K, Zhang ZX, Sakamoto Y, Kanda Y, Murakami K, Miyake A, Inoue M
1996年
The role of MAP kinase in oxytocin-induced contraction of rat pregnant uterine smooth muscle Biochem Biophys Res Commun 229: 938–944／ 英文学術誌／
Nohara A, Ohmichi M, Koike K, Masumoto N, Kobayashi M, Akabane M, Ikegami H, Hirota K, Miyake A, Murata Y
Endotoxin activates a chemokinergic neuronal pathway in the hypothalamo-pituitary system Endocrinology 137: 4503–4506／ 英文学術誌／
Sakamoto Y, Koike K, Kiyama H, Konishi K, Watanabe K, Osako Y, Hirota K, Miyake A
1995年
Perimenopausal changes in serum lipids and lipoproteins: A 7-year longitudinal study Maturitas 22: 193–199／ 英文学術誌／
Fukami K, Koike K, Hirota K, Yoshikawa H, Miyake A
Oxytocin stimulates MAP kinase activity in cultured human puerperal uterine myometrial cells Endocrinology 136: 2082–2087／ 英文学術誌／
Ohmichi M, Koike K, Nohara A, Kanda Y, Sakamoto Y, Zhang ZX, Hirota K, Miyake A
1994年
The production of CINC/GRO, a member of the interleukin-8 family, in rat anterior pituitary gland Biochem Biophys Res Commun 202: 161–167／ 英文学術誌／
Koike K, Sakamoto Y, Sawada T, Ohmichi M, Kanda Y, Nohara A, Hirota K, Kiyama H, Miyake A
Thyrotropin-releasing hormone stimulates MAP kinase activity in GH3 cells by divergent pathways: evidence of a role for early tyrosine phosphorylation J Biol Chem 269: 3783–3788／ 英文学術誌／
Ohmichi M, Sawada T, Kanda Y, Koike K, Hirota K, Miyake A, Saltiel AR
1993年
Prolactin stimulates [3H]dopamine release from dispersed rat tuberoinfundibular dopaminergic neurons and dopamine decreases gonadotropin-releasing hormone release induced by calcium ionophore Eur J Endocrinol 129: 548–553／ 英文学術誌／
Koike K, Kadowaki K, Hirota K, Ohmichi M, Ikegami H, Sawada T, Miyake A, Tanizawa O
Intraventricular administration of Histidyl-Proline-Diketopiperazine [Cyclo(His-Pro)] suppresses prolactin secretion and synthesis: a possible role as dopamine uptake blocker in rat hypothalamus Endocrinology 132: 953–958／ 英文学術誌／
Jikihara H, Ikegami H, Koike K, Wada K, Morishige K, Kurachi H, Hirota K, Miyake A, Tanizawa O
Effect of thyrotropin-releasing hormone and phorbol ester on dopamine release from dispersed rat tuberoinfundibular dopaminergic neurons Peptides 14: 839–844／ 英文学術誌／
Nishikawa Y, Ikegami H, Jikihara H, Koike K, Masumoto N, Kasahara K, Tasaka K, Hirota K, Miyake A, Tanizawa O
1992年
Atrial and brain natriuretic peptides enhance dopamine accumulation in cultured rat hypothalamic cells including dopaminergic neurons Neuroendocrinology 56: 11–17／ 英文学術誌／
Kadowaki K, Hirota K, Koike K, Ohmichi M, Miyake A, Tanizawa O
Intraventricular administration of thyrotrophin-releasing hormone suppresses prolactin secretion and synthesis: a possible involvement of dopamine release from rat hypothalamus J Endocrinol 133: 59–66／ 英文学術誌／
Ikegami H, Jikihara H, Koike K, Morishige K, Kurachi H, Yamamoto N, Hirota K, Miyake A, Tanizawa O
Immunohistochemical evidence that rat FSH cells contain βII-subspecies of protein kinase C Endocr J 39: 609–613／ 英文学術誌／
Ohmichi M, Hirota K, Koike K, Miyake A, Tanizawa O, Sato M, Tohyama M
1991年
Effect of prolactin on the secretion of hypothalamic GnRH and pituitary gonadotropins Horm Res 35: 5–12／ 英文学術誌／
Koike K, Miyake A, Aono T, Sakumoto T, Ohmichi M, Yamaguchi M, Tanizawa O
Tumor necrosis factor-α stimulates prolactin release from anterior pituitary cells: A possible involvement of intracellular calcium mobilization Endocrinology 128: 2785–2790／ 英文学術誌／
Koike K, Masumoto N, Kasahara K, Yamaguchi M, Tasaka K, Hirota K, Miyake A, Tanizawa O
Tumor necrosis factor-α increases release of arachidonate and prolactin from anterior pituitary cells Endocrinology 128: 2791–2798／ 英文学術誌／
Koike K, Hirota K, Ohmichi M, Kadowaki K, Ikegami H, Yamaguchi M, Miyake A, Tanizawa O
1990年
Dopamine inhibits TRH-induced MAP kinase activation in dispersed rat anterior pituitary cells Neuroendocrinology 52: 75–81／ 英文学術誌／
Ohmichi M, Hirota K, Koike K, Kadowaki K, Yamaguchi M, Miyake A, Tanizawa O
Interleukin-1 and tumor necrosis factor-α stimulate the release of gonadotropin-releasing hormone Eur J Endocrinol 123: 476–480／ 英文学術誌／
Yamaguchi H, Yoshimoto Y, Komura H, Koike K, Matsuzaki N, Hirota K, Miyake A, Tanizawa O
Adenosine 3′5′-cyclic monophosphate enhances dopamine accumulation in rat hypothalamic cell culture containing dopaminergic neurons Neuroendocrinology 52: 256–261／ 英文学術誌／
Kadowaki K, Hirota K, Koike K, Ohmichi M, Kiyama H, Miyake A, Tanizawa O
1989年
Involvement of extracellular calcium and arachidonate in [3H]dopamine release from rat tuberoinfundibular neurons Neuroendocrinology 50: 481–487／ 英文学術誌／
Ohmichi M, Hirota K, Koike K, Kadowaki K, Miyake A, Kiyama H, Tohyama M, Tanizawa O
A simple rapid method for prolactin assay by reversed passive hemagglutination: Evaluation of its clinical application Eur J Obstet Gynecol Reprod Biol 30: 279–284／ 英文学術誌／
Ohmichi M, Koike K, Miyake A, Tanizawa O
1988年
Possible involvement of lipoxygenase pathway of arachidonic acid in rat pituitary hormone release in vitro J Endocrinol Invest 11: 805–808／ 英文学術誌／
Miyake M, Nishizaki T, Ikegami H, Koike K, Hirota K, Tanizawa O
1987年
Relationship between the methods of treatment for prolactinomas and the puerperal lactation Fertil Steril 47: 867–869／ 英文学術誌／
Ikegami H, Aono T, Koizumi K, Koike K, Fukui H, Tanizawa O
1986年
Maitotoxin, a calcium channel activator, increases prolactin release from rat pituitary tumor 7315a cells by a mechanism that may involve leukotriene production Neuroendocrinology 43: 283–290／ 英文学術誌／
Koike K, Judd AM, Login IS, Yasumoto T, MacLeod RM
A possible role of arachidonate metabolism in the mechanism of prolactin release Am J Physiol 250: E288–295／ 英文学術誌／
Judd AM, Koike K, MacLeod RM
1985年
5-Hydroxyeicosatetraenoic acid increases prolactin release from rat anterior pituitary cells Endocrinology 116: 1813–1817／ 英文学術誌／
Koike K, Judd AM, MacLeod RM
Arachidonate stimulates prolactin release in vitro: a role for the fatty acid and its metabolites as intracellular regulators Endocrinology 116: 218–225／ 英文学術誌／
Canonico PL, Judd AM, Koike K, Schettini G, Valdenegro CA, MacLeod RM
1984年
Effect of pituitary transplants on the LH-RH concentrations in the medial basal hypothalamus and hypophyseal portal blood Brain Res 301: 253–258／ 英文学術誌／
Koike K, Aono T, Miyake A, Tasaka K, Chatani F, Kurachi K
1982年
Induction of ovulation in patients with normoprolactinemic amenorrhea by combined therapy with bromocriptine and clomiphene Fertil Steril 35: 138–141／ 英文学術誌／
Koike K, Aono T, Miyake A, Tsutsumi H, Matsumoto K, Kurachi K
Short feedback regulation of gonadotropin by prolactin Aono T, Miyake A, Koike K Role of Prolactin in Human Reproduction Karger, Basel／ ／p64–72
Modulation of anterior pituitary adenylate cyclase activity and prolactin secretion by maitotoxin, a calcium channel activator Schettini G, Hewlett EL, Cronin MJ, Koike K, Login IS, Judd AM, Yasumoto T, MacLeod RM Prolactin, Basic and Clinical Correlates Fidia Research Series, Vol.1, Section 3, Liviana Press, Padova／ ／p185–192
Dopamine decreases prolactin secretion induced by increases in calcium mobilization in the 7315a pituitary tumor, but not the MtTw15 pituitary tumor Judd AM, Koike K, Schettini G, Valdenegro CA, Hewlett EL, Yasumoto T, MacLeod RM Prolactin, Basic and Clinical Correlates Fidia Research Series, Vol.1, Section 3, Liviana Press, Padova／ ／p205–212
A possible role for diacylglycerol in regulating prolactin release from anterior pituitary cells Koike K, Judd AM, Yasumoto T, MacLeod RM Prolactin, Basic and Clinical Correlates Fidia Research Series, Vol.1, Section 3, Liviana Press, Padova／ ／p213–218
The role of phospholipid hydrolysis in the release of prolactin from anterior pituitary cells MacLeod RM, Judd AM, Koike K, Canonico PL, Login IS Endocrinology Excerpta Medica, Amsterdam–New York–Oxford／ ／p195–198
国際学会発表
2024年
Successful control of abnormal uterine bleeding by bazedoxifene acetate, a selective estrogen receptor modulator, during treatment of postmenopausal symptoms with transdermal hormone replacement therapy 16th World Congress on Menopause／ 国際学会発表／ Melbourne, Australia／
Tiger Koike, Koji Koike, Tomomi Shigaa, Motoki Takenaka, Tatsuro Furui
2016年
Efficacy of porcine placental extract on wrinkle widths below the eye in climacteric women 16th World Congress on Menopause／ 国際学会発表／ Prague, Czech Republic／
Koji Koike, Chikako Yoshikawa, Tiger Koike*, Fumihide Takano†, Nobutaka Suzuki
2014年
Efficacy of porcine placental extract on shoulder stiffness in climacteric and postmenopausal women with hormone therapy 14th World Congress on Menopause／ 国際学会発表／ Cancun, Mexico／
Tiger Koike, Koji Koike, Nobutaka Suzuki
2012年
Food and Nutrition for Woman’s Health in Modern World: Role of essence of chicken on brain health in climacteric women Cerebos Award Conference 2012／ 国際学会発表／ Bangkok, Thailand／
K Koike
2011年
Efficacy of porcine placental extracts as adjunctive treatment to hormone replacement therapy for postmenopausal women with knee pain 13th World Congress on Menopause／ 国際学会発表／ Roma, Italy／
Koji Koike, Nobutaka Suzuki, Kouichi Sugiura, Masaki Inoue
Efficacy of Brand’s Essence of chicken on climacteric symptoms in perimenopausal and postmenopausal women 5th Scientific Meeting on BRAND’S Essence of Chicken／ 国際学会発表／ Singapore／
Koji Koike
2009年
Ovariectomy causes hippocampal neuronal loss and cognitive dysfunction and restored by Ginkgo biloba extract EGb761 in rats 11th European Congress of Endocrinology／ 国際学会発表／ Istanbul, Turkey／
Koji Koike, Kazuhiro Takuma, Yuki Hoshina, Nobutaka Suzuki, Masaki Inoue, Kiyofumi Yamada
2006年
Efficacy of the Herbal Medicine Unkei-to as an Adjunctive Treatment to Hormone Replacement Therapy for Postmenopausal Women With Depressive Symptoms 12th World Congress of Gynecological Endocrinology／ 国際学会発表／ Florence, Italy／
Koike K, Suzuki N, Murakami K, Inoue M
